This model employed hydraulic suspension, which gave a smoother ride than the earlier 'spring- forked' bikes. It was one of the few Harley-Davidson models to be given a registered name - "Hydra-Glide".

The Panhead engine was introduced in 1948 and was quieter and cleaner than the Knucklehead which had been used since 1936.  The Knucklehead was named after the knuckle-like valve covers on the top of the engine.  The Panhead got its name from the large flat covers at the top of the cylinder heads. It had a better cooling system than the Knucklehead, as well as other modifications that reduced wear.  This made it easier to maintain.